Pharmacokinetics of Oral Prulifloxacin Capsules in Healthy Volunteers
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چکیده
منابع مشابه
Pharmacokinetics of Oral Taurine in Healthy Volunteers
Taurine, a sulfur-containing amino acid, is a normal constituent of the human diet. Little is known of the pharmacokinetics of taurine in man after oral administration. We studied the pharmacokinetics of 4 g taurine in eight healthy male volunteers (median age 27.5, range 22-45) following orally administration in the fasting state in the morning. Blood samples were taken at regular intervals an...
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Dronabinol is a pharmaceutical tetrahydrocannabinol originally developed as an oral capsule. A dronabinol oral solution was recently approved, and the effects of food on absorption and bioavailability of the oral solution versus capsules were compared in an open-label, single-dose, 3-period crossover study. Healthy volunteers were randomized to either dronabinol oral solution 4.25 mg (fed) or d...
متن کاملSingle dose pharmacokinetics of oral artemether in healthy Malaysian volunteers.
AIMS To determine the pharmacokinetics of artemether (ARM) and its principal active metabolite, dihydroartemisinin (DHA) in healthy volunteers. METHODS Six healthy male Malaysian subjects were given a single oral dose of 200 mg artemether. Blood samples were collected to 72 h. Plasma concentrations of the two compounds were measured simultaneously by reversed-phase h.p.l.c. with electro-chemi...
متن کاملBioequivalence Study of Two Formulations of Tramadol Capsules in Healthy Myanmar Volunteers
Background: Tramadol is one of the most commonly used analgesics, thanks to its efficacy and safety. It is widely used in Myanmar for postoperative and cancer pain control. The use of generic drugs has been steadily increasing worldwide, mostly in developing countries. Generic drugs should have efficacy and safety comparable to their innovators or other approved generic products. Objectives: ...
متن کاملFood interaction and steady-state pharmacokinetics of itraconazole capsules in healthy male volunteers.
The influence of food on itraconazole pharmacokinetics was evaluated for 27 healthy male volunteers in a single-dose (200 mg) crossover study with capsules containing itraconazole-coated sugar spheres. This study was followed by a study of the steady-state pharmacokinetics for the same subjects with 15 days of administration of itraconazole at 200 mg every 12 h. Concentrations of itraconazole a...
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ژورنال
عنوان ژورنال: Journal of Algorithms & Computational Technology
سال: 2011
ISSN: 1748-3026,1748-3026
DOI: 10.1260/1748-3018.5.1.111